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Lucy looking lovely

side Lucy

Ben at 5 years 1995

Ben at 5 yrs (2)

Cilla aged 9

side Cilla 2

Breed Record Holder 2009 - 2014

side Swann Cash

Ginny1985

side Tap 85

Harry on walk

side Harry

Gloria gets her CC

side Gloria

Kristen at Home

Kristen at Home

Maxinamilliion

side Max

Young Sparkey

Sparkey 3

Selina 2005

side  2005 2

Registering Hereditary Clear Puppies

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To register PLL hereditary clear puppies with the Kennel Club, so that the Puppies Registation Document states that the puppy is hereditary clear of PLL you must send the DNA test results of the sire and dam to the Kennel Club, either forward the emails you will have received from the Animal Health Trust stating that the sire and dam are clear, if you used someone elses dog (sire) they will also have had an email from the Animal Health Trust stating that the dog is clear.  You should forward this information to

[email protected]   

If you do not have a email adddress you will have received printed 'clear of PLL Certificates' from the Animal Health Trust, these should be sent to the Kennel Club registrations department.

 

DNA 'Research' Results 

 Dogs who have given blood at Lancashire Heeler Club shows over the years, these  results which are called 'research results' can be obtained free of charge by the owners of the dogs by applying to the Animal Health Trust

Symone Ingram
The Animal Health Trust
Genetics Services
Lanwades Park
Kennet
Newmarket
Suffolk
CB8 7UU

Tel: 01638 555621

These results will not be put onto the Kennel Club Databases as they have not been done under the BVA scheme, you would have to send the results you get from the Animal Health Trust to   

[email protected]   

 

 

This extract is taken from 'The Kennel Club Charitable Trust Update 2010'  published in June Lancashire Heelers tested to date are 80 of these 47 were clear 30 carriers and unfortunately 3 affected dogs. This is for dogs tested in the UK
 
The AHT had completed DNA tests for 2371 dogs, 8 different breeds, from 30 different countries.
 
 BREEDING ADVICE
 
The testing figures obtained to date indicate, that for some breeds at least,the percentage of dogs that carry the PLL mutation is extremely high.  For this reason the Animal Health Trust believes that eliminating all carriers from these breeding populations is inadvisable in the short term and advises breeders to consider all their dogs for breeding, regardless of their PLL genotype.  CARRIER dogs can be bred with, but should only be bred to DNA tested CLEAR dogs.  Because carriers are at a low risk of developing PLL we recommend that all puppies with a CARRIER parent should be DNA tested,
so that the CARRIERS can be identified and monitered clinically throughout their lives.  In exceptional circumstances GENETICALLY AFFECTED dogs may even be considered for breeding, if they are outstanding examples of the breedfor example, but, as with CARRIERS, should only be mated to CLEAR dogs. All offspring of a GENETICALLY AFFECTED parent will be CARRIERS, so should be clinically monitered throughtout their lives.  The practice of including CARRIERS for breeding should be followed for at least two generations, to allow the PLL mutation to be slowly eliminated from the population without severely reducing the genetic diversity of the breed.
 
Dr Catheryn Mellersh (Animal Health Trust) 
 
RESEARCH FINDINGS
 
PLL has long been considered to be a recessive condition, meaning that dogs need to inherit two copies of the causative mutation before they develop clinical signs of the condition.  Dogs that carry a single copy of a recessive mutation (herterozygotes) are free from clinical signs themselves but will pass the mutation onto approximately half of any offspring they have.  A surprising finding that emerged from the extensive research was that some dogs that carry a single copy of the PLL mutation develop bilateral PLL.  The exact number of carriers that develop PLL is difficult to estimate, for various reasons, including the fact that owners and breeders tend to tell researchers about their clinically affected dogs more often than they report their unaffected dogs.  However, we currently estimate that the percentage of carriers that develop clinical PLL is likely to be less than 5% in most breeds and understanding why some carriers develop PLL whereas the vast majority do not is the subject of continued investigation.
 
The 'clinically affected carrier phenomenon' is not restricted to a single breed: robust data is available from clinically affected carriers of at least six different breeds, indicating the phenomenon is real, and not restricted to single breeds, or isolated lines within breeds.
Golden Oldies

In these side panels are pics of dogs who are no longer shown, hope you enjoy seeing these oldies.

side Prince

Heskey by Hannie

Foxthyme Heskey 3

Taffy on his chair

Taffy on his chair

Sammy at home

Side Sammy

Breed Record Holder 2014

Ch Doddsline Daffodil at Welshmoor

Liver & Tan bitch

side Tammy

Pip about 1990

side Pip

Champion Oliver

side Oliver

Having a rest

side Hotpot

Lord at Show

Lord at Show

Tracy looking smart

Golden Oldies 10

Gladys having a look

side Gladys

Duke at Show

side Duke